Short answer is no - they take too much power and what happens is one may switch but not the other. I tried it with several of mine and the reliability was poor so I kept getting derailments when a point didn't change as expected. I concluded that two points would switch if both were very free-running, but any hint of stickinesss led to problems, especially as all of mine have the PL13 polarity switch fitted as well.
One solution is to use a DCC Concepts Masterswitch: this will happily switch at least two PL10 points but only needs one LS150 port. However, each Masterswitch costs slightly more than one LS150 port, so you are not saving money but you do gain a bit of operational simplicity. The Masterswitch Plus is also an option for crossovers as it also has 4 SPDT built in switches for frog polarity. It almost pays for itself as you save an LS150 port as well as 2 PL13 switches.
If you want to be able to change two points at once, then another solution is to connect each point to a port on separate LS150s, and assign each port the same number. However, this does require each LS150 to have its own power supply otherwise the same problem applies. I've got 11 LS150s on my layout and all are connected to one Lenz TR100 transformer: all works fine so long as I only change one point at a time. I'm using a computer with Traincontroller 5.8 to manage the signalling, with most points part of route setting, so I've now got no need to change two points at once.
